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Guangzhou HeaRan Biological Technology Co., Ltd.

Guangzhou HeaRan Biotechnology Co., Ltd. is a comprehensive enterprise that relies on high-tech biochemical technology and targeted micro-injection transmission patent technology, focusing on the development, production and sales of beauty cosmetics and health products. After continuous development and accumulation, our current business segment covers many fields such as beauty cosmetics, health care products, scientific and technical services, and the business network covers international markets such as China, North America and Europe.

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2015 year

HeaRan Biotechnology

was established in

20000

GMP standard production base

1000

The total Area of he R&D center

8 Person

There are 8 senior R&D engineers

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HEARAN OF BRANDS

 

XIZUN

Aiming at regional dullness and unevenness of skin tone, it purifies the skin texture, repairs uneven skin tone, and concentrates on improving and restoring skin's clarity, so that calm skin is gradually bright and clear. Aiming at regional dull and uneven skin tone, purify skin texture, repair skin color...

CUTEGO

Aiming at regional dullness and unevenness of skin tone, it purifies the skin texture, repairs uneven skin tone, and concentrates on improving and restoring skin's clarity, so that calm skin is gradually bright and clear. Aiming at regional dull and uneven skin tone, purify skin texture, repair skin color...

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PRODUCTS CENTER

Keratinocyte Growth Factor(KGF)
KGF(Keratinocyte Growth Factor) is produced by mesenchymal-derived cells and consists of 208 amino acid active polypeptides. It specifically acts on epithelial cells through the paracrine pathway but has no effect on fibroblasts and endothelial cells. It is is to promote the proliferation and development of epidermal cells. Biological function and mechanism 1.Prevent the formation of skin red blood. KGF- promotes the proliferation and differentiation of keratinocytes, repairs the stratum corneum of the skin, and effectively prevents the formation of red blood. 2.Repair cuticle function. It can greatly increase the proliferation of corneal cells and the migration of corneal cells, activate the mitogen protein kinase, and increase the activity of plasminogen activator, and accelerate the repair of damaged parts. 3.Maintain the normal shape of hair follicles and prevent thick hair follicles. Loss of KGF or loss of KGF receptors will lead to severe atrophy of the skin, abnormal hair follicle morphology, thickening of the dermis, and replacement of normal adipose tissue with uncovered tissue. HOW TO USE Add to the freeze-dried powder, essence or lotion, cream of cosmetics,have the effect of repairing sensitive skin and thickening keratin. HOW TO ADD It should be added in the last step of the essence or lotion and cream process, temperature of addition be lower than 30-35 degrees. It is recommended that the temperature of ingredients in freeze-dried powder should be lower than 16 degrees.
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Basic Fibroblast Growth Factor(bFGF)
bFGF (Basic Fibroblast Growth Factor) is a versatile cell growth factor composed of 146 amino acids and an active polypeptide with a molecular weight of 16.4KD. It plays an important role in promoting the growth of fibroblasts and other cells. Biological function and mechanism 1.Skin care and repair function. bFGF can improve the microenvironment of cell growth, promote the synthesis of elastic fibers and collagen, make the skin full of elasticity, and make the skin in a smooth and tender state. 2.Anti-wrinkle and anti-aging effects. It can promote the growth and development of fibroblasts, and constantly replace aging cells with new cells, so it has anti-wrinkle and anti-wrinkle effects. 3.Whitening and freckle removing effects. It can renew senescent cells thereby reduce the content of melanin and colored cells in skin cells, which reduce skin pigmentation. 4.Sunscreen and repair after sun exposure. It can quickly repair damaged cells and reduce the damage caused by ultraviolet radiation to the skin. 5.Anti-acne and scar removal effect. Stimulates the formation of granulation tissue in the skin and promotes the epithelialization of granulation tissue. It can also regulate the degradation and renewal of collagen, thereby shortening the time for wound healing and reducing scar formation. HOW TO USE It is recommended to be added to freeze-dried powder, essence, lotion or cream together with 0.1-0.3% HA (hyaluronic acid) and 0.1-0.5% vitamin E, which can have a stable effect. 2-3mg/kg of EGF can be compounded in the formula to enhance the anti-aging effect. For the improvement of stretch marks in medical beauty, it is recommended to compound aFGF 3mg/kg, bFGF 6mg/kg, blue copper peptide 5g/kg, and recombinant collagen 15mg/kg can gradually improve stretch marks. For true wrinkles, the recommended combination is aFGF 3mg/kg, bFGF 3mg/kg, blue copper peptide 3-5g/kg, and recombinant collagen 5-15mg/kg. HOW TO ADD bFGF is added in the last step of preparing of essence , lotion and cream. It is recommended to add in the temperature below 30-35 degrees. It is recommended that the temperature should not be higher than 16 degrees when preparing the ingredients of freeze-dried powder.
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Acidic Fibroblast Growth Factor (aFGF)
aFGF (acidic fibroblast growth factor) is a versatile and powerful cytokine, consisting of 141 amino acids and an active peptide with a molecular weight of 15.3KD. It plays an important role in promoting the metabolism of fibroblasts and the formation of collagen. Biological function and mechanism 1.Repair Mechanism: aFGF can actively combine with specific receptors on the cell membrane near the wound, thereby promoting cell division and proliferation, repairing wounds quickly and efficiently, such as thin skin after skin rejuvenation, rapid flushing fades, and rapid healing of wounds after removing acne.Remove spot and moles, remove wrinkles, wash eyebrows, plastic surgery wound healing. 2.Anti-wrinkle effect Mechanism: Through the three ways of skin renewal, maintaining skin elasticity, and supplementing skin nutrition, it can prevent and eliminate wrinkles. 3.Anti-spot effect Mechanism: aFGF replaces the original cells by promoting the formation of new cells to reduce the content of melanin and colored cells in the skin. In addition, by improving microcirculation to accelerate the metabolism of pigments, it is so as to achieve the effect of lightening pigments and rosy skin. 4.Sun protection Mechanism: aFGF is applied to the skin surface, which can reduce the damage of harmful ultraviolet bands to skin cells. HOW TO USE It is recommended to be added to freeze-dried powder, essence, lotion or cream together with 0.1-0.3% HA (hyaluronic acid) and 0.1-0.5% vitamin E, which can have a stable effect. 2-3mg/kg of EGF can be compounded in the formula to enhance the anti-aging effect. For the improvement of stretch marks in medical beauty, it is recommended to compound AFGF 3mg/kg, BFGF 6mg/kg, blue copper peptide 5g/kg, and recombinant collagen 15mg/kg can gradually improve stretch marks. For true wrinkles, the recommended combination are aFGF 3mg/kg, bFGF 3mg/kg, blue copper peptide 3-5g/kg, and recombinant collagen 5-15mg/kg. HOW TO ADD aFGF is added in the last step of preparing of essence , lotion and cream. It is recommended to add in the temperature below 30-35 degrees. It is recommended that the temperature should not be higher than 16 degrees when preparing the ingredients of freeze-dried powder.
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Epidermal Growth Factor (EGF)
EGF (Epidermal Growth Factor) is an active polypeptide composed of 53 amino acids with a molecular weight of 6.2KD, which is an important active protein peptide substance in the human body. Biological function and mechanism 1.Epidermal repair. Promote the growth, division and metabolism of epidermal cells and epithelial cells in the body, accelerate the repair of the epidermis and the reconstruction of the cuticle. 2.Whitening and rejuvenation. Promote new skin cells to replace and renew senescent cells can reduce the content of melanin and colored cells in skin cells and reduce skin pigmentation. HOW TO USE It is recommended to be added to freeze-dried powder, essence, lotion or cream. It is recommended to use together with 0.1-0.3% HA (hyaluronic acid) and 0.1-0.5% vitamin E, which can have a stable effect. HOW TO ADD EGF is added in the last step of preparing of essence , lotion and cream. It is recommended to add in the temperature below 30-35 degrees.  It is recommended that the temperature should not be higher than 16 degrees when preparing the ingredients of freeze-dried powder.
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R & D AND INNOVATION

Technology and Innovation Technology and Innovation
Technology and Innovation
Technology and Innovation
The R&D center covers a total area of 1000m², and now has a genetic engineering room, a pilot fermentation room, a protein separation and purification room, a preparation research room, a physical and chemical research room, a biological cosmetics research room, a cell culture room and a microbiological laboratory, etc.
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Research Team Research Team
Research Team
Research Team
The R&D center covers a total area of 1000m², and now has a genetic engineering room, a pilot fermentation room, a protein separation and purification room, a preparation research room, a physical and chemical research room, a biological cosmetics research room, a cell culture room and a microbiological laboratory, etc.
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Research Project Research Project
Research Project
Research Project
The R&D center covers a total area of 1000m², and now has a genetic engineering room, a pilot fermentation room, a protein separation and purification room, a preparation research room, a physical and chemical research room, a biological cosmetics research room, a cell culture room and a microbiological laboratory, etc.
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Scientific Research Results Scientific Research Results
Scientific Research Results
Scientific Research Results
The R&D center covers a total area of 1000m², and now has a genetic engineering room, a pilot fermentation room, a protein separation and purification room, a preparation research room, a physical and chemical research room, a biological cosmetics research room, a cell culture room and a microbiological laboratory, etc.
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Academic Exchange Academic Exchange
Academic Exchange
Academic Exchange
The R&D center covers a total area of 1000m², and now has a genetic engineering room, a pilot fermentation room, a protein separation and purification room, a preparation research room, a physical and chemical research room, a biological cosmetics research room, a cell culture room and a microbiological laboratory, etc.
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Industry-University-Research Alliance Industry-University-Research Alliance
Industry-University-Research Alliance
Industry-University-Research Alliance
The R&D center covers a total area of 1000m², and now has a genetic engineering room, a pilot fermentation room, a protein separation and purification room, a preparation research room, a physical and chemical research room, a biological cosmetics research room, a cell culture room and a microbiological laboratory, etc.
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PRODUCTIVE STRENGTH

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Production base

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GMP production base

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Freeze-dried powder production workshop

 

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Cosmetic workshop

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advanced equipment

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LATEST INFORMATION

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